OC 3.0.3.8
PHP 7.4
MAIL SMTP

The following is what is written in the 29th line indicated:
$header .= 'Reply-To: =?UTF-8?B?' . base64_encode($this->reply_to_sender) . '?=' . ' <' . $this->reply_to . '>' . PHP_EOL;
Thank you to everyone who is interested.