Create custom slideshow

how would i create a slideshow which is pushed to the left of the page. And then have 3 content boxes to the right of it which can be updated in the admin?

So the slideshow area looks like this website :

http://www.youngamerica.com/

The theme i plan on using is this one :

http://www.metagraphics.eu/modernstore/

Is this fairly straightforward, are there some modules etc to do this?